発表されましたね。macOS Sierra 。
さて、やはり気になるのはアプリの対応状況ですよね？MacRumorsのフォーラムにありましたよ！
ただし、開発者プレビュー版なので今後保障されるかはわかりません。
内容は今後、変わっていくとおもいますが、以下抜粋です。
互換性あり
1Password 6
2Do
Accordance Bible
Adapter
Adium (requires manual connection)
Adobe Acrobat Pro 10
Adobe Acrobat DC
Adobe InDesign CC (installs, but has some rendering issues when dragging objects)
Adobe Photoshop CC
Affinty Photo
Airmail 3
Alfred 3
Amphetamine
Aperture 3.6
BackBlaze 4.0.5.934
BetterTouchTool
Blackmagic Disk Speed Test
Caffeine
CARROT Weather
Chrome 51.0.2704.84
Cloudmagic
coconutBattery
Coda
Day One v2
Deliveries 2.0.1
Disk Inventory X
Downie 2.3.9
Drobo Dashboard
Dropbox
Duet (with iOS 10, although a bit choppy)
Evernote
Final Cut Pro X (launches but have not used)
FileZilla
Firefox
Flux
gfxCardStatus
Handbrake (launches but have not used)
HardwareGrowler
Hardware Monitor
iFlicks 2
iStat Menu 5.11
iStat Pro
Itsycal
Kodi
Letterspace v1.6.4
Magnet
Malwarebytes
Microsoft Office 2016
Mindnode
Minecraft 1.10
OmniFocus 2.5.3
OmniGraffle 6.0.4 (quite old)
OpenEmu
Opera
Outside 1.1.2
ownCloud Client 2.2.0
Parallels 11.2.0
PDF Expert
Pinegrow Web Editor v2.9
Pixelmator
Plex
Pocket 1.6.2
PopClip
Quicken 2007
QuickSleep 1.0.1
Reeder
Scrivener
ScummVM
Shazam
Sketch 3.8.3 by Bohemian Coding
Skitch 2.7.8
Spotify (although slow to launch and ever the memory hog)
Steam
StuffIt Expander
Text Expander 5.1.4
The Unarchiver
Transmission
Transmit
Tweetbot
Twitter
Vivaldi Web Browser (1.2.490.39) (64-bit)
VLC
VM Ware Fusion 8
Yummy FTP
XLD
互換性あり？？
Disk Sensei (launches but loses Trim support after restart)
Fusion 8.1.1 (see this post)
Simple Comic (will not install latest update but reads CBR files okay)
uTorrent (can crash in certain circumstances)
Logic Pro 9.1.8 (can crash intermittently)
互換性なし
Adobe Illustrator CS6 (installer error, if update from prior OS, make work after reinstall Java 6)
Adobe Photoshop CS6 (installer error, make work if update from prior OS)
Bartender 2 (crashes at launch)
BusyCal (crashes at launch)
Carbon Copy Cloner 4.19 (installs and opens for use but does not actually backup)
Citrix Receiver
CleanMyMac 3 (crashes at launch)
EtreCheck (crashes during scan)
Final Draft 9 (crashes at launch)
Fluid (any apps made with Fluid crash on startup)
Identify 551
LittleSnitch 3.6.3 (won’t launch)
Maintenance (crashes at launch)
Microsoft Office 2008 (crashes at launch)
Onyx (crashes at launch)
Pyware versions 8.0.0, 7, 6, and lower (due to Apple’s MRJ Java–not able to be installed on 10.12)
RapidWeaver 7 (Opens projects and appears to work but crashes when previewing Site)
Safari Technology Preview 9.1.2
Scansnap Manager (crashes while trying to save the PDF)
Telegram (crashes at launch)
Ulysses (crashes at launch)
Yosemite Disk Utility patched for El Capitan (crashes at launch)
Microsoft Onedrive (Crashes at Launch)
Western Digital Disk Tools (Complains about needing to be lauched from Applications folder)
Whatsapp Desktop (always recommends moving to Application folder when it is already there, and will lose login details prompting QR scans every time OS restarts)